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Centre warns against cough syrups for children under 2 years after deaths in two states



The advisory asked all healthcare facilities and clinical establishments to ensure the procurement and dispensing of products manufactured under Good Manufacturing Practices and formulated with pharmaceutical-grade excipients.”Sensitisation of prescribers and dispensers across public and private sectors is essential to uphold these standards of care. It is requested that all state/UT Health Departments, District Health Authorities, and all Clinical Establishments/healthcare facilities under your jurisdiction should implement and disseminate this advisory across government dispensaries, PHCs, CHCs, district hospitals, and medical institutions,” the advisory said.Earlier in the day, the health ministry said a joint team comprising representatives from the National Centre for Disease Control (NCDC), National Institute of Virology (NIV), Central Drugs Standard Control Organisation (CDSCO), among others, visited the site in Madhya Pradesh to collect samples of various cough syrups amid reports linking the recent deaths of children to the consumption of cough syrups.”According to the test results, none of the samples contained Diethylene Glycol (DEG) or Ethylene Glycol (EG), contaminants that are known to cause serious kidney injury,” the ministry said.The Madhya Pradesh State Food and Drug Administration (SFDA) also tested three samples and confirmed the absence of DEG/EG, it added.Further, blood/CSF samples were tested by the National Institute of Virology (NIV), Pune, for common pathogens.One case was found positive for Leptospirosis, the ministry said.Samples of water, entomological vectors, and respiratory specimens are under further investigation by National Environmental Engineering Research Institute (NEERI), NIV Pune, and other laboratories, it said.A multi-disciplinary team comprising experts from the National Centre for Disease Control (NCDC), NIV, Indian Council of Medical Research (ICMR), AIIMS-Nagpur, and state health authorities is investigating all possible causes behind the reported cases.On reports of two child deaths in Rajasthan because of contaminated cough syrup consumption, the ministry clarified that the product in question does not contain Propylene Glycol — a possible source of DEG/EG contamination, it said.Additionally, the product under reference is a Dextromethorphan-based formulation, which is not recommended for paediatric use, it said.



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